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Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion

Transactivation of EGF receptor (EGFR) by angiotensin II (Ang II) plays important roles in the initiation and progression of chronic kidney diseases. Studies suggest that heparin-binding EGF-like factor (HB-EGF) may be a critical mediator in this process, but its role in vivo has not been investigat...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Zeng, Fenghua, Kloepfer, Lance A., Finney, Charlene, Diedrich, André, Harris, Raymond C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142238/
https://ncbi.nlm.nih.gov/pubmed/27226110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00377.2015
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