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Influences of innate immunity, autophagy, and fibroblast activation in the pathogenesis of lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by accumulation of extracellular matrix (ECM) and impaired gas exchange. The pathobiological mechanisms that account for disease progression are poorly understood but likely involve alterations in innate inf...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: O'Dwyer, David N., Ashley, Shanna L., Moore, Bethany B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142210/
https://ncbi.nlm.nih.gov/pubmed/27474089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00221.2016
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