Interleukin-6 inhibition attenuates hypertension and associated renal damage in Dahl salt-sensitive rats

Immune cells in the kidney are implicated in the development of hypertension and renal damage in the Dahl salt-sensitive (SS) rat. Interestingly, interleukin 6 (IL-6) mRNA is 54-fold higher in T-lymphocytes isolated from the kidney compared with circulating T-lymphocytes. The present experiments ass...

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Bibliographic Details
Published in:Am J Physiol Renal Physiol
Main Authors: Hashmat, Shireen, Rudemiller, Nathan, Lund, Hayley, Abais-Battad, Justine M., Van Why, Scott, Mattson, David L.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142167/
https://ncbi.nlm.nih.gov/pubmed/27279492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00594.2015
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