Pharmacokinetic and pharmacodynamic characterization of a novel formulation containing co-formulated interferons alpha-2b and gamma in healthy male volunteers

BACKGROUND: More potent antitumor activity is desired in Interferon (IFN)-treated cancer patients. This could be achieved by combining IFN alpha and IFN gamma. The aim of this work was to characterize the pharmacokinetics and pharmacodynamics of a novel formulation containing a co-formulated combina...

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Publicado no:BMC Pharmacol Toxicol
Main Authors: García-García, Idrian, Hernández-González, Ignacio, Díaz-Machado, Alina, González-Delgado, Carlos A., Pérez-Rodríguez, Sonia, García-Vega, Yanelda, Campos-Mojena, Rosario, Tuero-Iglesias, Ángela D., Valenzuela-Silva, Carmen M., Cruz-Ramírez, Alieski, Martín-Trujillo, Alis, Santana-Milián, Héctor, López-Saura, Pedro A., Bello-Rivero, Iraldo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142133/
https://ncbi.nlm.nih.gov/pubmed/27923408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0103-8
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