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Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria

Background. Plasmodium infection depletes arginine, the substrate for nitric oxide synthesis, and impairs endothelium-dependent vasodilation. Increased conversion of arginine to ornithine by parasites or host arginase is a proposed mechanism of arginine depletion. Methods. We used high-performance l...

詳細記述

保存先:
書誌詳細
出版年:J Infect Dis
主要な著者: Alkaitis, Matthew S., Wang, Honghui, Ikeda, Allison K., Rowley, Carol A., MacCormick, Ian J. C., Chertow, Jessica H., Billker, Oliver, Suffredini, Anthony F., Roberts, David J., Taylor, Terrie E., Seydel, Karl B., Ackerman, Hans C.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142086/
https://ncbi.nlm.nih.gov/pubmed/27923948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw452
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