In silico Screening and Evaluation of the Anticonvulsant Activity of Docosahexaenoic Acid-Like Molecules in Experimental Models of Seizures

BACKGROUND: Resistance to antiepileptic drugs and the intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid (DHA) make it as a good candidat...

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發表在:Iran Biomed J
Main Authors: Loron, Ali Gharibi, Sardari, Soroush, Narenjkar, Jamshid, Sayyah, Mohammad
格式: Artigo
語言:Inglês
出版: Pasteur Institute 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141252/
https://ncbi.nlm.nih.gov/pubmed/27592363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/.21.1.32
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