Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor.

By screening a cDNA library derived from the A10 rat vascular smooth muscle cell line for functional expression in COS cells, we have isolated a high-affinity receptor for endothelin 1 (Kd = 476 pM) and endothelin 2. The affinity of the cloned endothelin receptor for endothelin 3 is greater than 100...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Lin, H Y, Kaji, E H, Winkel, G K, Ives, H E, Lodish, H F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1849646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3185
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