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Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53

Invasive growth and apoptosis resistance of breast cancer cells are associated with metastasis and disease relapse. Here we identified that the lysine-specific demethylase KDM3A played a dual role in breast cancer cell invasion and apoptosis by demethylating histone and the non-histone protein p53,...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Ramadoss, Sivakumar, Guo, Gao, Wang, Cun-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140781/
https://ncbi.nlm.nih.gov/pubmed/27270439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.174
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