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Chronic HIV-1 infection impairs superantigen-induced activation of peripheral CD4+CXCR5+PD-1+ cells, with relative preservation of recall antigen-specific responses
Peripheral CD4+CXCR5+PD-1+ T cells are a putative circulating counterpart to germinal center T follicular helper (T(FH)) cells. They show both phenotypic and functional similarities to T(FH) cells, which provide necessary help for the differentiation of B cells to antibody-secreting plasmablasts. In...
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| Publicado no: | J Acquir Immune Defic Syndr |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5140753/ https://ncbi.nlm.nih.gov/pubmed/27509243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001152 |
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