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Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization

Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with increased risk of cerebrovascular stroke, and with several other pathologies, including heart failure. Current therapies for AF are targeted at reducing risk of stroke (anticoagulation) and tachycardia-induced cardiomyo...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Grandi, Eleonora, Maleckar, Mary M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140742/
https://ncbi.nlm.nih.gov/pubmed/27612549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2016.09.012
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