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Chronological Lifespan in Yeast Is Dependent on the Accumulation of Storage Carbohydrates Mediated by Yak1, Mck1 and Rim15 Kinases

Upon starvation for glucose or any other macronutrient, yeast cells exit from the mitotic cell cycle and acquire a set of characteristics that are specific to quiescent cells to ensure longevity. Little is known about the molecular determinants that orchestrate quiescence entry and lifespan extensio...

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Publicat a:PLoS Genet
Autors principals: Cao, Lu, Tang, Yingzhi, Quan, Zhenzhen, Zhang, Zhe, Oliver, Stephen G., Zhang, Nianshu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140051/
https://ncbi.nlm.nih.gov/pubmed/27923067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006458
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