Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer

Some 15–20% of multiple adenomatous polyposis have no genetic explanation and 20–30% of colorectal cancer (CRC) cases are thought to be due to inherited multifactorial causes. Accumulation of deleterious effects of low-frequency dominant and independently acting variants may be a partial explanation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Hum Genet
Main Authors: Lefevre, Jérémie H, Bonilla, Carolina, Colas, Chrystelle, Winney, Bruce, Johnstone, Elaine, Tonks, Susan, Day, Tammy, Hutnik, Katarzyna, Boumertit, Abdelhamid, Soubrier, Florent, Midgley, Rachel, Kerr, David, Parc, Yann, Bodmer, Walter F
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140019/
https://ncbi.nlm.nih.gov/pubmed/22875147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2012.99
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados