DNA methylation in lung cells is associated with asthma endotypes and genetic risk

The epigenome provides a substrate through which environmental exposures can exert their effects on gene expression and disease risk, but the relative importance of epigenetic variation on human disease onset and progression is poorly characterized. Asthma is a heterogeneous disease of the airways,...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Nicodemus-Johnson, Jessie, Myers, Rachel A., Sakabe, Noburu J., Sobreira, Debora R., Hogarth, Douglas K., Naureckas, Edward T., Sperling, Anne I., Solway, Julian, White, Steven R., Nobrega, Marcelo A., Nicolae, Dan L., Gilad, Yoav, Ober, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139904/
https://ncbi.nlm.nih.gov/pubmed/27942592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90151
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