DNA methylation in lung cells is associated with asthma endotypes and genetic risk

The epigenome provides a substrate through which environmental exposures can exert their effects on gene expression and disease risk, but the relative importance of epigenetic variation on human disease onset and progression is poorly characterized. Asthma is a heterogeneous disease of the airways,...

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Vydáno v:JCI Insight
Hlavní autoři: Nicodemus-Johnson, Jessie, Myers, Rachel A., Sakabe, Noburu J., Sobreira, Debora R., Hogarth, Douglas K., Naureckas, Edward T., Sperling, Anne I., Solway, Julian, White, Steven R., Nobrega, Marcelo A., Nicolae, Dan L., Gilad, Yoav, Ober, Carole
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139904/
https://ncbi.nlm.nih.gov/pubmed/27942592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90151
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