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Dataset of eye disease-related proteins analyzed using the unfolding mutation screen

A number of genetic diseases are a result of missense mutations in protein structure. These mutations can lead to severe protein destabilization and misfolding. The unfolding mutation screen (UMS) is a computational method that calculates unfolding propensities for every possible missense mutation i...

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Vydáno v:Sci Data
Hlavní autoři: McCafferty, Caitlyn L., Sergeev, Yuri V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139671/
https://ncbi.nlm.nih.gov/pubmed/27922631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2016.112
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