Functional impairment of infiltrating T cells in human colorectal cancer

T cells play a crucial role in preventing the growth and spread of colorectal cancer (CRC). However, immunotherapies against CRC have only shown limited success, which may be due to lack of understanding about the effect of the local tumor microenvironment (TME) on T cell function. The goal of this...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Taylor, Edward S., McCall, John L., Girardin, Adam, Munro, Fran M., Black, Michael A., Kemp, Roslyn A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139627/
https://ncbi.nlm.nih.gov/pubmed/27999752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1234573
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