Functional impairment of infiltrating T cells in human colorectal cancer

T cells play a crucial role in preventing the growth and spread of colorectal cancer (CRC). However, immunotherapies against CRC have only shown limited success, which may be due to lack of understanding about the effect of the local tumor microenvironment (TME) on T cell function. The goal of this...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Taylor, Edward S., McCall, John L., Girardin, Adam, Munro, Fran M., Black, Michael A., Kemp, Roslyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139627/
https://ncbi.nlm.nih.gov/pubmed/27999752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1234573
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