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Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I

Crude Amaryllidaceae alkaloids (AAs) extracted from Lycoris radiata are reported to exhibit significant anti-cancer activity. However, the specific alkaloids responsible for the pharmacodynamic activity and their targets still remain elusive. In this context, we strived to combine affinity ultrafilt...

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Foilsithe in:Sci Rep
Main Authors: Chen, Gui-Lin, Tian, Yong-Qiang, Wu, Jian-Lin, Li, Na, Guo, Ming-Quan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138836/
https://ncbi.nlm.nih.gov/pubmed/27922057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38284
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