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Mitogen-activated protein kinases (MAPKs) are modulated during Francisella tularensis infection, but inhibition of extracellular-signal-regulated kinases (ERKs) is of limited therapeutic benefit

Francisella tularensis is a Gram-negative intracellular bacterium that causes the disease tularemia. The disease can be fatal if left untreated and there is currently no licenced vaccine available; the identification of new therapeutic targets is therefore required. Toll-like receptors represent an...

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Detalhes bibliográficos
Publicado no:Eur J Clin Microbiol Infect Dis
Main Authors: Saint, R. J., D’Elia, R. V., Bryant, C., Clark, G. C., Atkins, H. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138274/
https://ncbi.nlm.nih.gov/pubmed/27714591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10096-016-2754-1
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