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Regulation of gap junction conductance by calcineurin through Cx43 phosphorylation: implications for action potential conduction

Cardiac arrhythmias are associated with raised intracellular [Ca(2+)] and slowed action potential conduction caused by reduced gap junction (GJ) electrical conductance (Gj). Ventricular GJs are composed of connexin proteins (Cx43), with Gj determined by Cx43 phosphorylation status. Connexin phosphor...

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Bibliografski detalji
Izdano u:Pflugers Arch
Glavni autori: Jabr, Rita I, Hatch, Fiona S, Salvage, Samantha C, Orlowski, Alejandro, Lampe, Paul D, Fry, Christopher H
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138272/
https://ncbi.nlm.nih.gov/pubmed/27757582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1885-7
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