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Histone Deacetylase Inhibitors Reduce the Number of Herpes Simplex Virus-1 Genomes Initiating Expression in Individual Cells

Although many viral particles can enter a single cell, the number of viral genomes per cell that establish infection is limited. However, mechanisms underlying this restriction were not explored in depth. For herpesviruses, one of the possible mechanisms suggested is chromatinization and silencing o...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Shapira, Lev, Ralph, Maya, Tomer, Enosh, Cohen, Shai, Kobiler, Oren
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138200/
https://ncbi.nlm.nih.gov/pubmed/27999572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01970
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