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Clinical activity of regorafenib in PDGFRA-mutated gastrointestinal stromal tumor

Gastrointestinal stromal tumor (GIST) is the most frequent mesenchymal tumor of the gastrointestinal tract and one of the most frequent sarcoma. Mutually exclusive KIT and PDGFRA mutations are central events in GIST pathogenesis, and their understanding is crucial because specific treatment targetin...

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Foilsithe in:Future Sci OA
Main Authors: Grellety, Thomas, Kind, Michèle, Coindre, Jean-Michel, Italiano, Antoine
Formáid: Artigo
Teanga:Inglês
Foilsithe: Future Science Ltd 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137998/
https://ncbi.nlm.nih.gov/pubmed/28031906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fso.15.33
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