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The case of galantamine: repurposing and late blooming of a cholinergic drug
Galantamine is a reversible inhibitor of cholinesterases and an allosteric modulator of neuronal nicotinic acetylcholine receptors which restores reduced cholinergic tone in the central and peripheral nervous system. Characterized in the early 1950s in Bulgaria, it saw limited use for paralytic and...
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| Publicat a: | Future Sci OA |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Future Science Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137937/ https://ncbi.nlm.nih.gov/pubmed/28031923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fso.15.73 |
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