Extracellular embryo genomic DNA and its potential for genotyping applications

BACKGROUND: Preimplantation genetic diagnosis (PGD) currently relies on biopsy of one or few embryo cells. Our aim was to evaluate the embryo extracellular matrices (spent medium and blastocoele fluid) as source of DNA for embryo genotyping. RESULTS/METHODOLOGY: We first evaluated the amplifiability...

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Detalhes bibliográficos
Publicado no:Future Sci OA
Main Authors: Galluzzi, Luca, Palini, Simone, Stefani, Silvia De, Andreoni, Francesca, Primiterra, Mariangela, Diotallevi, Aurora, Bulletti, Carlo, Magnani, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2015
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137924/
https://ncbi.nlm.nih.gov/pubmed/28031914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fso.15.62
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