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Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor

Ring-shaped hexameric helicases and translocases support essential DNA-, RNA-, and protein-dependent transactions in all cells and many viruses. How such systems coordinate ATPase activity between multiple subunits to power conformational changes that drive the engagement and movement of client subs...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Thomsen, Nathan D., Lawson, Michael R., Witkowsky, Lea B., Qu, Song, Berger, James M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137716/
https://ncbi.nlm.nih.gov/pubmed/27856760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616745113
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