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Pembrolizumab (Keytruda)
The programmed cell death protein 1 (PD1) is one of the checkpoints that regulates the immune response. Ligation of PD1 with its ligands PDL1 and PDL2 results in transduction of negative signals to T-cells. PD1 expression is an important mechanism contributing to the exhausted effector T-cell phenot...
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| Publicado no: | Hum Vaccin Immunother |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137544/ https://ncbi.nlm.nih.gov/pubmed/27398650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1199310 |
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