Ancillary contributions of heterologous biotin protein ligase and carbonic anhydrase for CO(2) incorporation into 3-hydroxypropionate by metabolically engineered Pyrococcus furiosus

Acetyl-Coenzyme A carboxylase (ACC), malonyl-CoA reductase (MCR), and malonic semialdehyde reductase (MRS) convert HCO(3)(−) and acetyl-CoA into 3-hydroxypropionate (3HP) in the 3-hydroxypropionate/4-hydroxybutyrate carbon fixation cycle resident in the extremely thermoacidophilic archaeon Metallosp...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Lian, Hong, Zeldes, Benjamin M., Lipscomb, Gina L., Hawkins, Aaron. B., Han, Yejun, Loder, Andrew J., Nishiyama, Declan, Adams, Michael W.W., Kelly, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137508/
https://ncbi.nlm.nih.gov/pubmed/27315782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26033
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