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Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design
Zika virus has attracted increasing attention because of its potential for causing human neural disorders, including microcephaly in infants and Guillain–Barré syndrome. Its NS3 helicase domain plays critical roles in NTP-dependent RNA unwinding and translocation during viral replication. Our struct...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137455/ https://ncbi.nlm.nih.gov/pubmed/27915293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw941 |
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