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Codon usage is less optimized in eukaryotic gene segments encoding intrinsically disordered regions than in those encoding structural domains

Codon usage tends to be optimized in highly expressed genes. A plausible explanation for this phenomenon is that translational accuracy is increased in highly expressed genes with infrequent use of rare codons. Besides structural domains (SDs), eukaryotic proteins generally have intrinsically disord...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Homma, Keiichi, Noguchi, Tamotsu, Fukuchi, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137448/
https://ncbi.nlm.nih.gov/pubmed/27915289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw899
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