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Structural basis of the disorder in the tandem zinc finger domain of the RNA-binding protein Tristetraprolin

Tristetraprolin (TTP) and TIS11d are two human RNA-binding proteins that belong to the CCCH-type tandem zinc finger family. In the RNA-free state, TIS11d coordinates a zinc ion in each of its two fingers, while TTP coordinates a single zinc ion with the N-terminal zinc finger. We have previously ide...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Tavella, Davide, Deveau, Laura M., Whitfield, Troy W., Massi, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137377/
https://ncbi.nlm.nih.gov/pubmed/27487322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b00150
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