Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (CbpL) Contributing to Pneumococcal Pathogenesis

The human pathogen Streptococcus pneumoniae is decorated with a special class of surface-proteins known as choline-binding proteins (CBPs) attached to phosphorylcholine (PCho) moieties from cell-wall teichoic acids. By a combination of X-ray crystallography, NMR, molecular dynamics techniques and in...

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Publicado no:Sci Rep
Main Authors: Gutiérrez-Fernández, Javier, Saleh, Malek, Alcorlo, Martín, Gómez-Mejía, Alejandro, Pantoja-Uceda, David, Treviño, Miguel A., Voß, Franziska, Abdullah, Mohammed R., Galán-Bartual, Sergio, Seinen, Jolien, Sánchez-Murcia, Pedro A., Gago, Federico, Bruix, Marta, Hammerschmidt, Sven, Hermoso, Juan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137146/
https://ncbi.nlm.nih.gov/pubmed/27917891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38094
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