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Hippocampal proteomics defines pathways associated with memory decline and resilience in ‘normal’ aging and Alzheimer’s disease mouse models

Alzheimer’s disease (AD), the most common form of dementia in the elderly, has no cure. Thus, the identification of key molecular mediators of cognitive decline in AD remains a top priority. As aging is the most significant risk factor for AD, the goal of this study was to identify altered proteins...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Neuner, Sarah M., Wilmott, Lynda A., Hoffmann, Brian R., Mozhui, Khyobeni, Kaczorowski, Catherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135662/
https://ncbi.nlm.nih.gov/pubmed/27265785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.06.002
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