Insights into Nucleosome Organization in Mouse Embryonic Stem Cells through Chemical Mapping

Nucleosome organization influences gene activity by controlling DNA accessibility to transcription machinery. Here, we develop a chemical biology approach to determine mammalian nucleosome positions genome-wide. We uncovered surprising features of nucleosome organization in mouse embryonic stem cell...

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Publicat a:Cell
Autors principals: Voong, Lilien N., Xi, Liqun, Sebeson, Amy C., Xiong, Bin, Wang, Ji-Ping, Wang, Xiaozhong
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135608/
https://ncbi.nlm.nih.gov/pubmed/27889238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.049
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