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The intracellular cholesterol landscape: dynamic integrator of the immune response

Cholesterol has typically been considered an exogenous, disease-related factor in immunity; however, recent literature suggests that a paradigm shift is in order. Sterols are now recognized to ligate several immune receptors. Altered flux through the mevalonic acid synthesis pathway also appears to...

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Bibliographic Details
Published in:Trends Immunol
Main Author: Fessler, Michael B.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135597/
https://ncbi.nlm.nih.gov/pubmed/27692616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2016.09.001
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