HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia

The hemochorial placenta develops from the coordinated multilineage differentiation of trophoblast stem (TS) cells. An invasive trophoblast cell lineage remodels uterine spiral arteries, facilitating nutrient flow, failure of which is associated with pathological conditions such as preeclampsia, int...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Chakraborty, Damayanti, Cui, Wei, Rosario, Gracy X., Scott, Regan L., Dhakal, Pramod, Renaud, Stephen J., Tachibana, Makoto, Rumi, M. A. Karim, Mason, Clifford W., Krieg, Adam J., Soares, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135375/
https://ncbi.nlm.nih.gov/pubmed/27807143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612626113
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