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Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis
A barrier to drug development for nonalcoholic steatohepatitis (NASH) is the absence of translational preclinical human-relevant systems. An in vitro liver model was engineered to incorporate hepatic sinusoidal flow, transport, and lipotoxic stress risk factors (glucose, insulin, free fatty acids) w...
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| Publicado en: | JCI Insight |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5135271/ https://ncbi.nlm.nih.gov/pubmed/27942596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90954 |
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