Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other neurodevelopment defects remain poorly understood. Here, we describe the derivation and characterization, including single-cell RNA-seq, of neocortical and spinal cord neuroepithelial stem (NES) cells to model early human neu...

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Publicat a:Cell Rep
Autors principals: Onorati, Marco, Li, Zhen, Liu, Fuchen, Sousa, André M.M., Nakagawa, Naoki, Li, Mingfeng, Dell’Anno, Maria Teresa, Gulden, Forrest O., Pochareddy, Sirisha, Tebbenkamp, Andrew T.N., Han, Wenqi, Pletikos, Mihovil, Gao, Tianliuyun, Zhu, Ying, Bichsel, Candace, Varela, Luis, Szigeti-Buck, Klara, Lisgo, Steven, Zhang, Yalan, Testen, Anze, Gao, Xiao-Bing, Mlakar, Jernej, Popovic, Mara, Strittmatter, Stephen M., Kaczmarek, Leonard K., Anton, E. S., Horvath, Tamas L., Lindenbach, Brett D., Sestan, Nenad
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135012/
https://ncbi.nlm.nih.gov/pubmed/27568284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.038
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