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Push-pull and feedback mechanisms can align signaling system outputs with inputs

Many cell signaling systems, including the yeast pheromone response system, exhibit “dose-response alignment” (DoRA), in which output of one or more downstream steps closely matches the fraction of occupied receptors. DoRA can improve the fidelity of transmitted dose information. Here, we searched s...

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Detalles Bibliográficos
Publicado en:Cell Syst
Main Authors: Andrews, Steven S., Peria, William J., Yu, Richard C., Colman-Lerner, Alejandro, Brent, Roger
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134923/
https://ncbi.nlm.nih.gov/pubmed/27894998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.10.002
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