The Power of an Adaptive Trial Design for Endovascular Stroke Studies: Simulations Using IMS III Data

BACKGROUND AND PURPOSE: Adaptive trial designs that allow enrichment of the study population through subgroup selection can increase the chance of a positive trial when there is a differential treatment effect among patient subgroups. The goal of this study is to illustrate the potential benefit of...

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Bibliographic Details
Published in:Stroke
Main Authors: Lansberg, Maarten G., Bhat, Ninad S., Yeatts, Sharon D, Palesch, Yuko Y, Broderick, Joseph P, Albers, Gregory W, Lai, Tze L., Lavori, Philip W.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134921/
https://ncbi.nlm.nih.gov/pubmed/27895297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.015436
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