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Distinct immunological activation profiles of dSLIM® and ProMune® depend on their different structural context
INTRODUCTION: DNA‐based TLR9 agonists are potent activators of the immune system. ProMune® and dSLIM® belong to different families of TLR9 agonists and both have been established as cancer immunotherapeutics in clinical proof‐of‐concept studies. Unfortunately, ProMune® failed in pivotal oncological...
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| Publicado no: | Immun Inflamm Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5134728/ https://ncbi.nlm.nih.gov/pubmed/27980779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.126 |
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