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Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA.

Constructs expressing the core, surface, X, or polymerase proteins of hepatitis B virus were transfected into human cells. In transient assays, only the polymerase inhibited the responses to interferons alpha and gamma (IFN-alpha and -gamma). Stable expression of the polymerase was achieved in the c...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Foster, G R, Ackrill, A M, Goldin, R D, Kerr, I M, Thomas, H C, Stark, G R
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51345/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1707174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.7.2888
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