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Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice

The aim of this study was to investigate the effect of testosterone and oestrogen on regulating organic cation transporters (Octs) and multidrug and toxin extrusions (Mates) expression in the kidney of mice and urinary excretion of metformin. 8 week‐old male db/db mice were treated with estradiol (5...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: He, Rui, Ai, Ligen, Zhang, Dandan, Wan, Lili, Zheng, Taishan, Yin, Jun, Lu, Huijuan, Lu, Junxi, Lu, Fengdi, Liu, Fang, Jia, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134372/
https://ncbi.nlm.nih.gov/pubmed/27469532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12922
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