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Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors

Radiation therapy is commonly used to treat patients with head and neck squamous cell carcinoma (HNSCC). One of the major side effects of radiotherapy is injury to the salivary glands (SG), which is thought to be mediated by microvascular dysfunction leading to permanent xerostomia. The goal of this...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Mizrachi, Aviram, Cotrim, Ana P., Katabi, Nora, Mitchell, James B., Verheij, Marcel, Haimovitz-Friedman, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134326/
https://ncbi.nlm.nih.gov/pubmed/27459704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14431.1
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