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Uncovering the mechanisms of Caenorhabditis elegans ageing from global quantification of the underlying landscape

Recent studies on Caenorhabditis elegans reveal that gene manipulations can extend its lifespan several fold. However, how the genes work together to determine longevity is still an open question. Here we construct a gene regulatory network for worm ageing and quantify its underlying potential and f...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Zhao, Lei, Wang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134008/
https://ncbi.nlm.nih.gov/pubmed/27903783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2016.0421
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