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Uncovering the mechanisms of Caenorhabditis elegans ageing from global quantification of the underlying landscape

Recent studies on Caenorhabditis elegans reveal that gene manipulations can extend its lifespan several fold. However, how the genes work together to determine longevity is still an open question. Here we construct a gene regulatory network for worm ageing and quantify its underlying potential and f...

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Bibliografiske detaljer
Udgivet i:J R Soc Interface
Main Authors: Zhao, Lei, Wang, Jin
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134008/
https://ncbi.nlm.nih.gov/pubmed/27903783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2016.0421
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