PARP1 regulates the protein stability and proapoptotic function of HIPK2

Homeodomain-interacting protein kinase 2 (HIPK2) is a nuclear serine/threonine kinase that functions in DNA damage response and development. In the present study, we propose that the protein stability and proapoptotic function of HIPK2 are regulated by poly(ADP-ribose) polymerase 1 (PARP1). We prese...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Choi, Jong-Ryoul, Shin, Ki Soon, Choi, Cheol Yong, Kang, Shin Jung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134000/
https://ncbi.nlm.nih.gov/pubmed/27787517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.345
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