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Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model

Therapy-related cancers are potentially fatal late life complications for patients who received radio- or chemotherapy. So far, the mouse model showing reduction or delay of these diseases has not been described. We found that the disruption of Aplf in mice moderately attenuated DNA damage repair an...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Tong, Kit I, Ota, Kazushige, Komuro, Akiyoshi, Ueda, Takeshi, Ito, Akihiko, Anne Koch, C, Okada, Hitoshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133969/
https://ncbi.nlm.nih.gov/pubmed/27711078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.298
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