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Stearoyl-CoA Desaturase-1 Protects Cells against Lipotoxicity-Mediated Apoptosis in Proximal Tubular Cells

Saturated fatty acid (SFA)-related lipotoxicity is a pathogenesis of diabetes-related renal proximal tubular epithelial cell (PTEC) damage, closely associated with a progressive decline in renal function. This study was designed to identify a free fatty acid (FFA) metabolism-related enzyme that can...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Iwai, Tamaki, Kume, Shinji, Chin-Kanasaki, Masami, Kuwagata, Shogo, Araki, Hisazumi, Takeda, Naoko, Sugaya, Takeshi, Uzu, Takashi, Maegawa, Hiroshi, Araki, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133868/
https://ncbi.nlm.nih.gov/pubmed/27834856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111868
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