IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells

The IBTK gene encodes the major protein isoform IBTKα that was recently characterized as substrate receptor of Cul3-dependent E3 ligase, regulating ubiquitination coupled to proteasomal degradation of Pdcd4, an inhibitor of translation. Due to the presence of Ankyrin-BTB-RCC1 domains that mediate se...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Fiume, Giuseppe, Scialdone, Annarita, Rizzo, Francesca, De Filippo, Maria Rosaria, Laudanna, Carmelo, Albano, Francesco, Golino, Gaetanina, Vecchio, Eleonora, Pontoriero, Marilena, Mimmi, Selena, Ceglia, Simona, Pisano, Antonio, Iaccino, Enrico, Palmieri, Camillo, Paduano, Sergio, Viglietto, Giuseppe, Weisz, Alessandro, Scala, Giuseppe, Quinto, Ileana
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133848/
https://ncbi.nlm.nih.gov/pubmed/27827994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111848
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