IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells

The IBTK gene encodes the major protein isoform IBTKα that was recently characterized as substrate receptor of Cul3-dependent E3 ligase, regulating ubiquitination coupled to proteasomal degradation of Pdcd4, an inhibitor of translation. Due to the presence of Ankyrin-BTB-RCC1 domains that mediate se...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Fiume, Giuseppe, Scialdone, Annarita, Rizzo, Francesca, De Filippo, Maria Rosaria, Laudanna, Carmelo, Albano, Francesco, Golino, Gaetanina, Vecchio, Eleonora, Pontoriero, Marilena, Mimmi, Selena, Ceglia, Simona, Pisano, Antonio, Iaccino, Enrico, Palmieri, Camillo, Paduano, Sergio, Viglietto, Giuseppe, Weisz, Alessandro, Scala, Giuseppe, Quinto, Ileana
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133848/
https://ncbi.nlm.nih.gov/pubmed/27827994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111848
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