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Effect of High-Carbohydrate Diet on Plasma Metabolome in Mice with Mitochondrial Respiratory Chain Complex III Deficiency

Mitochondrial disorders cause energy failure and metabolic derangements. Metabolome profiling in patients and animal models may identify affected metabolic pathways and reveal new biomarkers of disease progression. Using liver metabolomics we have shown a starvation-like condition in a knock-in (Bcs...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Rajendran, Jayasimman, Tomašić, Nikica, Kotarsky, Heike, Hansson, Eva, Velagapudi, Vidya, Kallijärvi, Jukka, Fellman, Vineta
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133825/
https://ncbi.nlm.nih.gov/pubmed/27809283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111824
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