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Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway

H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed regions of mRNA genes, repressing internal cryptic promoters and slowing elongation. Here we explore the function of this pathway by analysing transcription in yeast undergoing a series of carbon source shifts. Approximately...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Ji Hyun, Lee, Bo Bae, Oh, Young Mi, Zhu, Chenchen, Steinmetz, Lars M., Lee, Yookyeong, Kim, Wan Kyu, Lee, Sung Bae, Buratowski, Stephen, Kim, TaeSoo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133700/
https://ncbi.nlm.nih.gov/pubmed/27892458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13534
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