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Rac1-NADPH oxidase signaling promotes CD36 activation under glucotoxic conditions in pancreatic beta cells

We recently reported that cluster determinant 36 (CD36), a fatty acid transporter, plays a pivotal role in glucotoxicity-induced β-cell dysfunction. However, little is known about how glucotoxicity influences CD36 expression. Emerging evidence suggests that the small GTPase Rac1 is involved in the p...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Elumalai, Suma, Karunakaran, Udayakumar, Lee, In Kyu, Moon, Jun Sung, Won, Kyu Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133656/
https://ncbi.nlm.nih.gov/pubmed/27912197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.11.009
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