A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells

Renal tumour-initiating cells (T-ICs) contribute to tumorigenesis, progression and drug resistance of renal cell carcinoma (RCC). However, the underlying mechanism for the propagation of renal T-ICs remains unclear. Here we show that long non-coding RNA lncARSR is upregulated in primary renal T-ICs...

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Udgivet i:Nat Commun
Main Authors: Qu, Le, Wu, Zhenjie, Li, Yaoming, Xu, Zhipeng, Liu, Bing, Liu, Feng, Bao, Yi, Wu, Dengshuang, Liu, Jiayi, Wang, Anbang, Chu, Xiaoyuan, Sun, Yinghao, Chen, Cheng, Zhang, Zhengyu, Wang, Linhui
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133634/
https://ncbi.nlm.nih.gov/pubmed/27886176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12692
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